In vitro antimicrobial activity of douro wines against clinical Helicobacter Pylori Strains
نویسندگان
چکیده
Aim. In vitro antimicrobial activities of seven wines (5 reds and 2 whites) from the Douro region (Iberian Peninsule) against eleven clinical strains Helicobacter pylori were evaluated.
 Methods. The disk diffusion method, using Columbia Agar supplemented with horse blood (CAB), used to determine properties some wine components H. strains. Potential interactions antioxidants contained in two antimicrobials (amoxicillin metronidazole) studied by method.
 Results. All tested showed growth CAB 9% but none them grew media 45% 67.5% wine. Similarly, all concentration proanthocyanidins present different types wines. Minimal Inhibitory Concentration (MIC) values antioxidant (benzoic acid, catechin, quercetin, resveratrol) indicate that resveratrol was most powerful inhibitory substance pylori. An effect potentiation between amoxicillin metronidazole also established. interaction or catechin increased activity pylori.
 Conclusions. results obtained suggested a potential role as chemopreventive agent for infection.
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ژورنال
عنوان ژورنال: Nova
سال: 2021
ISSN: ['1794-2470', '2462-9448']
DOI: https://doi.org/10.22490/24629448.5499